What We Do
Transformative, Keratin-Based Solutions
KeraNetics™ delivers transformative keratin-based solutions to support injured or compromised skin and other tissues.
We have ongoing sponsored research with academic and industry partners to conduct developmental work, pre-clinical trials, and human clinical trials for each of our technologies.
Focus Areas
- KeraStat® Cream: Radiation dermatitis applications for patients receiving radiotherapy for head, neck, throat, breast, and skin cancer.
- KeraStat® Wound Care: Trauma applications for burn and wound management, small molecule delivery, and radiation injury.
- KeraGenics Tissue Regeneration: Small molecule delivery vehicles and platform applications to support muscle repair and nerve regeneration.
- cGMP Manufacturing: Production of purified keratin proteins.
- Research and Development: Cutting edge innovation and advancement in the applications of keratin proteins.
Radiation dermatitis (RD; also known as radiation-induced dermatitis or radiation induced skin injury or radiation burn) is a term used to describe a spectrum of common skin reactions, or skin toxicities that are caused by radiation therapy.
The stages of RD have been well-defined and progress in a predictable, radiation dose-dependent manner1. As early as the first dose of radiation therapy, when the cumulative radiation dose is still low, mild reactions such as skin redness (i.e., erythema) can occur. As you receive more and more treatments, moderate reactions such as dry, flaky skin (i.e., dry desquamation) and severe reactions such as oozing skin (i. e., moist desquamation) may appear2. It is possible to have some radiation dermatitis symptoms occur a few weeks or months after your last treatment3.
As mentioned, symptoms and their progression (stages) are quite predictable. What is not predictable is who will exhibit symptoms of RD and who will not. Health care providers (HCPs) recognize that physiological differences in people make it difficult to predict or pinpoint those who are susceptible to radiation dermatitis symptoms.
Your HCP will typically suggest that you keep the radiated area clean with warm water and fragrance-free soap. Your provider may also suggest prophylactic (preventative) use of products to reduce or delay the effects of radiation dermatitis. Consult with your health care provider to see if applying KeraStat® Cream after your first radiation dose is right for you and your radiation therapy journey.
- Kole AJ, Kole L, Moran MS. Acute radiation dermatitis in breast cancer patients: challenges and solutions. Breast Cancer – Targets and Therapy. 2017;9:313-323. PMID 38503074.
- Leventhal J, Young MR. Radiation dermatitis: recognition, prevention, and management. Oncology. 2017 Dec 15;31(12):885-7, 894-9. PMID 29297172.
- Iacovelli NA, Torrente Y, Ciuffreda A, et al. Topical treatment of radiation-induced dermatitis: current issues and potential solutions. Drugs in Context 2020;9:2020-4-7. 2020 PMID 32587626.
